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Valcyte helps prevent cytomegalovirus (CMV) disease in adult and pediatric transplant patients who have a high chance of developing CMV disease after receiving a heart, kidney, or kidney-pancreas transplant.

The Valcyte Co-pay Card Program closed to new enrollments on May 1, 2020.

For patients currently enrolled, the Valcyte Co-pay Card Program will continue to process claims received prior to November 30, 2020 that meet co-pay eligibility requirements.

Valcyte will continue to be included in the Genentech Access to Care Foundation (GATCF) Patient Assistance Program for patients who meet specific income, medical and insurance eligibility guidelines. To speak with a GATCF specialist, call 1-888-754-7651 Monday - Friday.


What is VALCYTE?

VALCYTE® is a prescription antiviral medicine.

In adults, VALCYTE tablets are used:

  • to treat cytomegalovirus (CMV) retinitis in people who have acquired immunodeficiency syndrome (AIDS). When CMV virus infects the eyes, it is called CMV retinitis. If CMV retinitis is not treated, it can cause blindness.
  • to prevent CMV disease in people who have received a kidney, heart, or kidney-pancreas transplant and who have a high risk for getting CMV disease.

VALCYTE does not cure CMV retinitis. You may still get retinitis or worsening of retinitis during or after treatment with VALCYTE. It is important to stay under a healthcare provider's care and have your eyes checked at least every 4 to 6 weeks during treatment with VALCYTE.

In children, VALCYTE tablets or oral solution are used:

  • to prevent CMV disease in children 4 months to 16 years of age who have received a kidney transplant and have a high risk for getting CMV disease.
  • to prevent CMV disease in children 1 month to 16 years of age who have received a heart transplant and have a high risk for getting CMV disease.

It is not known if VALCTYE is safe and effective in children for prevention of CMV disease in liver transplant, in kidney transplant in infants less than 4 months of age, in heart transplant in infants less than 1 month of age, in children with AIDS who have CMV retinitis, and in infants with congenital CMV infection.


What is the most important information I should know about VALCYTE?

VALCYTE can cause serious side effects, including:

  • Blood and bone marrow problems. VALCYTE can affect the bone marrow lowering the amount of your white blood cells, red blood cells, and platelets and may cause serious and life-threatening problems.
  • Kidney failure. Kidney failure may happen in people who are elderly, people who take VALCYTE with certain other medicines, or people who are not adequately hydrated.
  • Fertility problems. VALCYTE may lower sperm count in males and cause fertility problems. VALCYTE may also cause fertility problems in women. Talk to your healthcare provider if this is a concern for you.
  • Birth defects. VALCYTE causes birth defects in animals. It is not known if VALCYTE causes birth defects in people. If you are a female who can become pregnant, you should use effective birth control during treatment with VALCYTE and for at least 30 days after treatment. If you are pregnant, talk to your healthcare provider before starting treatment with VALCYTE. If you are a female who can become pregnant, you should have a pregnancy test done before starting VALCYTE.
    • Tell your healthcare provider right away if you become pregnant during treatment with VALCYTE.
    • Males should use condoms during treatment with VALCYTE, and for at least 90 days after treatment, if their female sexual partner can become pregnant. Talk to your healthcare provider if you have questions about birth control.
  • Cancer. VALCYTE causes cancer in animals and may potentially cause cancer in people.

Your healthcare provider will do regular blood test during treatment with VALCYTE to check you for side effects. Your healthcare provider may change your dose or stop treatment with VALCYTE if you have serious side effects.

Do not take VALCYTE if you have had a serious allergic reaction to valganciclovir, ganciclovir or any of the ingredients of VALCYTE.

What should I tell my doctor before taking VALCYTE?

Before you take VALCYTE, tell your healthcare provider about all of your medical conditions, including if you:

  • have low blood cell counts
  • have kidney problems
  • are receiving hemodialysis
  • are receiving radiation treatment
  • are pregnant or plan to become pregnant. See "What is the most important information I should know about VALCYTE?"
  • are breastfeeding or plan to breastfeed. It is not known if VALCYTE passes into your breast milk. You should not breastfeed if you take VALCYTE.
    • You should not breastfeed if you have Human Immunodeficiency Virus (HIV-1) because of the risk of passing HIV-1 to your baby.
    • Talk to your healthcare provider about the best way to feed your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. VALCYTE and other medicines may affect each other and cause serious side effects. Keep a list of your medicines to show your healthcare provider and pharmacist.

  • You can ask your healthcare provider or pharmacist for a list of medicines that interact with VALCYTE.
  • Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take VALCYTE with other medicines.

How should I take VALCYTE?

  • Take VALCYTE exactly as your healthcare provider tells you. Your dose of VALCYTE will depend on your medical condition.
  • Adults should only take VALCYTE tablets. Children may take either VALCYTE tablets or oral solution.
  • Take VALCYTE with food.
  • Do not break or crush VALCYTE tablets. Avoid contact with your skin or eyes. If you come in contact with the contents of the tablet or oral solution, wash your skin well with soap and water or rinse your eyes well with plain water.
  • If your child is prescribed VALCYTE for oral solution, your pharmacist will give you oral dosing dispensers to measure your child's dose of VALCYTE for oral solution. To be sure you receive the prescribed dose, it is important to use the dispenser provided to you. See the detailed Instructions for Use for information about how to take VALCYTE for oral solution. Ask your pharmacist if you have any questions. If you lose or damage your oral dispensers and cannot use them, contact your pharmacist.
  • If you take too much VALCYTE, call your healthcare provider or go to the nearest hospital emergency room right away.

What should I avoid during treatment with VALCYTE?

VALCYTE can cause seizures, dizziness, and confusion. You should not drive a car or operate machinery until you know how VALCYTE affects you.

What are the possible side effects of VALCYTE?

VALCYTE may cause serious side effects, including:

See "What is the most important information I should know about VALCYTE?"

The most common side effects of VALCYTE in adults include:

  • diarrhea
  • fever
  • fatigue
  • nausea
  • shaky movements (tremors)
  • low white cell, red cell, and platelet cell counts in blood tests
  • headache
  • sleeplessness
  • urinary tract infection
  • vomiting

The most common side effects of VALCYTE in children include:

  • diarrhea
  • fever
  • upper respiratory tract infection
  • urinary tract infection
  • vomiting
  • low white blood cell counts in blood tests
  • headache

These are not all of the possible side effects of VALCYTE. Tell your doctor about any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to the US Food & Drug Administration (FDA) at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.

Terms and Conditions

This Valcyte Co-pay Program is valid ONLY for patients with commercial (private or non-governmental) insurance who have a valid prescription for a Food and Drug Administration (FDA)-approved indication of a Genentech medication. Patients using Medicare, Medicaid, Medigap, Veteran's Affairs (VA), Department of Defense (DoD), TRICARE or any other federal or state government program to pay for their medications are not eligible. The Program is not valid for medications that are eligible to be reimbursed in their entirety by private insurance plans or other programs.

Under the Program, the patient will pay a co-pay. After reaching the maximum Program benefit, the patient will be responsible for all Out-of-Pocket costs. This Program is not health insurance or a benefit plan. The Program does not obligate the use of any specific product or provider. Patients receiving assistance from charitable assistance programs (such as Genentech Patient Foundation) are not eligible. The Co-pay benefit cannot be combined with any other rebate, free trial, or similar offer for the medication. No party may seek reimbursement for all or any part of the benefit received through this Program.

The Program may be accepted by participating pharmacies, physician offices, or hospitals. Once enrolled, this Program will not honor claims with date of service or medication dispensing that precede Program enrollment by more than 120 days. Use of this Program must be consistent with all relevant health insurance requirements. Participating patients, pharmacies, physician offices, and hospitals are responsible for reporting the receipt of all Program benefits as required by any insurer or by law. Program benefits may not be sold, purchased, traded, or offered for sale, purchase, or trade.

The patient or their guardian must be 18 years or older for the patient to be eligible. This Program is only valid in the United States and U.S. Territories. This Program is void where prohibited by law and shall follow state restrictions in relation to AB-rated generic equivalents (e.g. MA, CA) where applicable. Program eligibility is contingent upon the patient's ability to meet and maintain all requirements set forth by the Program. Genentech reserves the right to rescind, revoke, or amend the Program without notice at any time.